USPeptideRx Learn
The rules behind clinic compounding, quoted from the source.
Explainers for physicians, clinic operators and telehealth teams on how compounding regulation is actually written — verbatim rule text, primary-source citations, and an honest account of what each page could not establish.
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Definitions
503A vs 503B
Two different statutory bargains. A 503A pharmacy is exempt from current good manufacturing practice and pays for it with the patient-specific prescription requirement; a 503B outsourcing facility does the reverse.
Compliance
Office-use compounding by state
Whether a clinic may stock compounded medications, compared across every state reviewed. The answers range from outright prohibition to a non-sterile-only permission with a mandatory label legend.
Regulatory explainer
What actually happened to peptides in 2026
Three separate events have been reported as one story: a set of withdrawn nominations, a consultation that has not happened, and a rulemaking that is not final. Only one kind of event changes a list, and none of these did.
Status tracker
Compounding status tracker
Which federal pathway applies to each substance under section 503A and, separately, under section 503B — every row dated to the day its FDA source was read.
Glossary
The terms, and who decides them
Office use, 503A, 503B, beyond-use date, cGMP, non-resident licence and the USP chapters — each defined from the rule that defines it, and each with the body that actually decides whether it binds anyone. It is almost never the one whose name is on the term.
Workflow
How to place an office-use order
What an office-use order carries, what the supplier is required to ask you for, and which answers from a supplier should end the conversation.
Data
Reference tables, with their retrieval dates
Every board of pharmacy and its licence-lookup portal, and where FDA-registered outsourcing facilities are. Each table carries the date its source was read and states what it cannot tell you.
By practice type
What blocks your kind of practice
Med spas, telehealth operators, hormone and weight-management clinics, nurse-practitioner-owned practices and solo prescribers each hit a different binding constraint. Each page leads with the one that is not the others’.
Ordering workflow
How clinics order compounded medications
The whole sequence, from opening an account to what a pharmacy verifies about a prescriber, what documents it asks for, which orders can travel out of an EMR, and what changes the moment a second state is involved.
Comparisons
Two things wearing one name
A prescription delivered to your office is not office stock, a compounded preparation is not a generic, and a registered outsourcing facility is not a drug manufacturer. Each page names the fact that separates the pair.
Operator Q&A
The questions operators actually ask
Whether office use is legal, whether a med spa may hold stock, what a nurse practitioner may order, and what changes across a state line — each with the rule that decides it.
State rules
Reviewed 2026-08-28. Each page quotes the governing rule verbatim.
Georgia
GAProhibited (human prescribers)North Carolina
NCPermitted under state pharmacy law, conditioned on federal lawOhio
OHNarrow statutory carve-out; legally contestedLouisiana
LANot authorised for human office use; veterinary onlyNew Jersey
NJProhibited (human), sterile and non-sterileIllinois
ILPermitted for non-sterile only; sterile prohibitedArizona
AZHuman office use ends September 5, 2026 — veterinary only from that dateCalifornia
CAStatute permits; the implementing regulation was repealedColorado
CORepealed in 2021; veterinary onlyFlorida
FLNot authorised for human office use; veterinary onlyNew York
NYNo 503A office-use provision; office use is an outsourcing-facility termTexas
TXPermitted by Texas pharmacy law; no federal condition attachedPennsylvania
PANo state office-use rule; federal section 503A governs by referenceMichigan
MINarrow — a discretionary state authorization naming one pharmacy and one prescriberWashington
WAPermitted only by negative implication, with an unresolved licensure question underneathVirginia
VANarrow — a critical need to treat an emergency condition, or as federal law allowsTennessee
TNNarrow — only when the product is not commercially availableMinnesota
MNProhibited (human) — all compounding must be for a specific patientSouth Carolina
SCPermitted by South Carolina pharmacy law; no federal condition attachedAlabama
ALPermitted by Alabama pharmacy law; no federal condition attachedMaryland
MDNarrow — ophthalmologists only, two drug classes, six named conditionsMissouri
MOProhibited (human); the office-stock pathway is veterinary onlyWisconsin
WINo office-use rule in force — repealed 2025-10-01, replacement still pendingIndiana
INBarred for compounding from bulk drug substances; no office-use permission existsNevada
NVRepealed in 2024 for compounded drugs; manufactured office supplies unaffectedConnecticut
CTSplit by sterility — non-sterile expressly permitted, sterile patient-specific onlyOklahoma
OKBoth compounding office-use rules revoked; a narrow non-compounding supply lane survivesKentucky
KYSilent by expiry — the human rule lapsed in 2020 and only a veterinary rule replaced itOregon
ORReclassified as manufacturing, not permitted; the only express office-use limb is nuclearIowa
IABarred for 503A product by definition — office use is defined as outsourcing-facility supplyKansas
KSPermitted by Kansas pharmacy rules, sterile and non-sterile alike; no federal condition attachedNebraska
NEPermitted by Nebraska statute as a co-equal purpose of compounding; no federal condition attachedUtah
UTPermitted by statute, conditioned on federal law by the implementing ruleArkansas
ARSilent for 503A pharmacies; expressly permitted for outsourcing facilities since 2025Mississippi
MSNon-patient-specific supply prohibited; patient-specific office administration expressly permittedNew Mexico
NMSilent on the human side; two express veterinary grants sit beside itMassachusetts
MANot prohibited — redefined: doing it makes the supplier an outsourcing facility by statuteNew Hampshire
NHExpressly permitted by statute, but only for products that are not commercially availableMaine
MEBarred by a closed statutory definition; the only non-patient-specific limb is veterinaryRhode Island
RIBarred for pharmacies twice over — and outsourcing facilities are carved out by nameVermont
VTNo human non-patient-specific limb; veterinary office use expressly permitted, including resaleDelaware
DEClosed to pharmacies and open to outsourcing facilities, in one sentence beginning "Only"North Dakota
NDPermitted by rule, but only from an outsourcing facility or a resident North Dakota pharmacyIdaho
IDGenuinely split: an express statutory office-use exception against a patient-specific definition of compoundingMontana
MTSilent in Montana’s own law; the only reachable office-use words are federal, and a rulemaking is pendingSouth Dakota
SDNo authorising rule and no express prohibition; closed by the structure of the rules, as an inferenceWyoming
WYExpressly invalid for a pharmacy, in those words; the same two words are compulsory on an outsourcing facility’s labelWest Virginia
WVNot established — the statute is silent and the operative rule has not been readAlaska
AKPermitted by exception — in a board pamphlet incorporated by reference, not in the codeHawaii
HISilent in both directions; non-patient-specific supply falls outside the prescription exclusionDistrict of Columbia
DCNo office-use provision; supplying a practitioner reclassifies the pharmacy as a wholesaler, and there is no outsourcing-facility class to route it to
Ordering through licensed pharmacies
USPeptideRx connects physicians and clinics to licensed 503A compounding pharmacies and FDA-registered 503B outsourcing facilities — patient-specific prescriptions or office stock, on one account.
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